mapt — TargetMol Chemicals

Cat No.	Product Name	Synonyms
T34132	Primapterin	L-Erythro-7-isobiopterin,7-Isobiopterin
	Primapterin, 7-Substituted pterins, is a new type of mammalian pteridines.
T81865	MAPTAM
	MAPTAM is an intracellular Ca^2+ (Ca 2+) chelator [1].
T64256	Emapticap pegol
	Emapticap pegol is a pro-inflammatory chemokine C-C motif ligand 2 (CCL2) inhibitor. emapticap pegol is also a 40-nucleotide oligonucleotide aptamer that exhibits different forms of Spiegelmers (L-RNA aptamers) in human ...
T73992	IONIS-MAPTRx
	IONIS-MAPTRx (BIIB080) is the first Tau-lowering antisense oligonucleotide (ASO). IONIS-MAPTRx has the potential for the research of Alzheimer Disease [1] . ( MCE IONIS-MAPTRx for murine use [3] : Tau ASO-12 sequence – 5...
T80616	Posdinemab
	Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].

Compounds

Primapterin

T34132

Synonym: L-Erythro-7-isobiopterin,7-Isobiopterin

Cat No.	Product Name	Synonyms	Targets
T11060	DMAPT	Dimethylamino Parthenolide	NF-κB
	DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03425	Tau Protein, Human, Recombinant (His)	Human	E. coli
	MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
TMPJ-00828	Tau-F Protein, Human, Recombinant	Human	E. coli
	Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons...
TMPJ-00827	Tau-D Protein, Human, Recombinant (His)	Human	E. coli
	Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ...
TMPH-00009	OGT Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc...
TMPJ-01076	FKBP4 Protein, Human, Recombinant (His)	Human	E. coli
	FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone recepto...
TMPH-02229	TRA2B Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne...
TMPH-02228	TRA2B Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne...
TMPH-01683	Tau Protein, Human, Recombinant (HEK293, His)	Human	HEK293
	Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane com...
TMPH-02275	Lck Protein, Human, Recombinant (His)	Human	E. coli
	Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TC...
TMPH-01692	MAPK3 Protein, Human, Recombinant (His)	Human	E. coli
	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate...
TMPH-02479	PRKAA1 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activat...
TMPH-02478	PRKAA1 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus
	Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activat...