lr3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22698	TLR3-IN-1	CU CPT 4a	TLR
	TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cell...
T69221	BMS-554417
	BMS-554417 is a novel inhibitor of IGF-IR, which inhibits IGF-IR and insulin receptor kinase activity and proliferation in vitro, and reduces tumor xenograft size in vivo. In a series of carcinoma cell lines, the IC50 fo...

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04942	IGF1 LR3 Protein, Human, Recombinant	Human	P. pastoris (Yeast)
	IGF1 LR3 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 9.1 kDa and the accession number is P05019-1.
TMPJ-00781	LR3-IGF-1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-termin...
TMPK-00740	LRP-5 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ...
TMPK-00739	LRP-5 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ...
TMPY-06639	LRP-5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LRP-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.21 kDa and the accession number is O75197-1.
TMPY-04722	DcR1/TRAILR3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most ...
TMPY-01396	TLR3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TLR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.7 kDa and the accession number is Q99MB1.
TMPH-01247	POLR3K Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs....
TMPK-00544	TLR3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	TLR3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 78.04 kDa and the accession number is A0A2K5WT39.
TMPK-00406	TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 78.7 kDa and the accession number is Q6PCD4.
TMPK-00878	FOLR3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Folic acid and folate receptors (FOLRs) play an important role in the downregulation of homocysteine (Hcy), a risk factor of Alzheimer's disease, thrombosis, neuropsychiatric illness and fractures.
TMPY-06410	TLR3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	TLR3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 79.38 kDa and the accession number is Q6PCD4.
TMPH-01246	POLR3A Protein, Human, Recombinant (His)	Human	E. coli
	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs,...