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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T64096 | Integrase-LEDGF/p75 allosteric inhibitor 1 | ||
Integrase-LEDGF/p75 allosteric inhibitor 1 is an orally active integrase-LEDGF/p75 (IN-LEDGF/p75) allosteric inhibitor. It inhibits HIV-1 DNA integration and exhibits antiviral effects, acting on the HIV-1 recombinant mo... | |||
T4182 | Lavendustin B | Tyrosinase , transporter , HIV Protease | |
Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75). | |||
T39755 | Pirmitegravir | STP0404 | HIV Protease |
Pirmitegravir (STP0404) is a potent and selective inhibitor of allosteric integrase (ALLINI) targeting the LEDGF/p75 binding site. Pirmitegravir inhibits PBMC. Pirmitegravir inhibits PBMC.Pirmitegravir has significant an... | |||
T17314 | (±)-BI-D | Others | |
(±)-BI-D is an effective ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site (IC50: 2.4–2.9 μM). | |||
T69782 | GS-9822 | ||
GS-9822 is a novel LEDGIN, an inhibitor that targets the binding pocket of LEDGF/p75 which is a cellular cofactor that substantially contributes to HIV integration site selection, displaying a block-and-lock phenotype in... |