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Search Results for " ldhb "

Targets

6

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T4295 (R)-GNE-140 GNE-140 Dehydrogenase
(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.
T11829 LDH-IN-1 Dehydrogenase
LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).
T15435 GSK2837808A Dehydrogenase
GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).
T22336 Galloflavin Dehydrogenase
Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. Galloflavin is also a potential anticancer agent.
T61539 AXKO-0046
AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.
T81747 MS6105 PROTACs
MS6105 is a chimeric LDH protein hydrolysis-targeted PROTAC that degrades LDHA and LDHB efficiently, with its activity contingent on both time and the ubiquitin-proteasome system, exhibiting anticancer properties [1]. Ad...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00797 LDHB Protein, Human, Recombinant (His) Human E. coli
L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LD...
TargetMol