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LDH-IN-1

Catalog No. T11829 CAS 1964515-43-2

Purity 99.84% Datasheet

LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).

LDH-IN-1, CAS 1964515-43-2

Pack Size	Availability	Price/USD
1 mg	In stock	277.00
5 mg	In stock	565.00
10 mg	In stock	876.00
25 mg	In stock	1807.00
50 mg	In stock	2841.00
100 mg	In stock	4082.00
1 mL * 10 mM (in DMSO)	In stock	780.00

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Purity 99.84%

HNMR HPLC COA Datasheet

Biological Description

Chemical Properties

Storage & Solubility Information

Description	LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).
Targets&IC50	LDHA :ic50 32 nM, LDHB :ic50 27 nM,
In vitro	LDH-IN-1 exhibit low nM inhibition of both LDHA and LDHB, submicromolar inhibition of lactate production, and inhibition of glycolysis in MiaPaCa2 pancreatic cancer and A673 sarcoma cells.

Molecular Weight	570.68
Formula	C30H26N4O4S2
CAS No.	1964515-43-2

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

0. Rai G, et al. Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J Med Chem. 2017 Nov 22;60(22):9184-9204. 1. Rai G, et al. Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J Med Chem. 2017 Nov 22;60(22):9184-9204.

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Tech Support

Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.