kpc — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN6733	Kansuiphorin C	KPC	Others
	Kansuiphorin C (KPC) is a natural product with a number of bioactivity. KPC could ameliorate malignant ascites by modulating gut microbiota mainly containing the increase of Lactobacillus and the decrease of Helicobacter...		Others
T60470	KPC-2-IN-2
	KPC-2-IN-2 (Compound 6c) is a potent Klebsiella pneumoniae carbapenemase (KPC-2) inhibitor with Ki of 0.038 μM. KPC-2-IN-2 can enhance the activity of cefotaxime in E. coli expressing KPC-2 [1].
T74917	KPC-2-IN-1
	KPC-2-IN-1, a boronic acid derivative, serves as an effective KPC-2 inhibitor with a K i of 0.032 μM, augmenting cefotaxime's efficacy against KPC-2 expressing E. coli. It demonstrates good tolerance in human HEK-293 cel...
T23801	WCK-4234 sodium	WCK-4234,WCK4234,WCK 4234	Antibacterial
	WCK-4234 sodium (WCK 4234) is an inhibitor of β-lactamase can be used in studies targeting MDR infections. WCK-4234 sodium inhibits class A, C, and D β-lactamases and OXA carbapenemases.		Antibacterial
T13077	Taniborbactam dihydrochloride	VNRX-5133 dihydrochloride,Taniborbactam 2HCl	Antibacterial , Antifungal
	Taniborbactam dihydrochloride (VNRX-5133 dihydrochloride) is a selective and potent novel cyclic boronic acid β-lactamase inhibitor with antimicrobial activity and significant inhibition of Gram-negative bacteria.Tanibor...		Antibacterial , Antifungal
T11125	Durlobactam sodium salt	ETX2514 sodium salt	Antibacterial
	Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be u...		Antibacterial
T4201	Avibactam sodium	AVE-1330A,NXL-104	Antibacterial , Antibiotic
	Avibactam sodium (NXL-104) is a reversible β-lactamase inhibitor (IC50: 8/80/38 nM, for TEM-1/P99/KPC-2 β-lactamases).		Antibacterial , Antibiotic
T17210L	Vaborbactam ammonium salt	RPX7009 ammonium salt,Vaborbactam ammonium salt（1360457-46-0 Free base）	Antibacterial
	Vaborbactam ammonium salt is a β-lactamase inhibitor that restores carbapenem activity against KPC-producing strains and is often used in conjunction with other drugs to study fungal infections.		Antibacterial
T60050	ANT3310		Antibacterial
	ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection.		Antibacterial
T13077L	Taniborbactam	VNRX-5133	Antibacterial
	Taniborbactam is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor (IC50s: 8-530 nM). Taniborbactam has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2.		Antibacterial
T39758	ARX-1796	ARX-1796,AV-006
	ARX-1796 (AV-006), an Avibactam prodrug, is an orally bioavailable β-lactamase inhibitor. Avibactam has a spectrum of inhibition of class A and C β-lactamases, including ESBLs, AmpC and Klebsiella pneumoniae carbapenemas...