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Search Results for " kbp "

Targets

12

Compounds

13

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T27715 KBP-7018 KBP 7018
KBP-7018 is a potent, selective tyrosine kinase inhibitor with effects on three fibrotic kinases c-KIT, RET, and PDGFR (IC50 values are 10nM, 7.6 nM and 25nM respectively).
T70382 KBP-7018 HCl
KBP-7018 Hydrochloride is a novel, tyrosine kinase-selective inhibitor with potent effects on three fibrotic kinases (c-KIT, PDGFR, and RET).
T80731 Zifanocycline TFA KBP-7072 TFA
Zifanocycline (KBP-7072) TFA is a semi-synthetic aminomethylcycline antibiotic with oral bioavailability, targeting bacterial ribosomes to impede their function. Displaying a broad spectrum of in vitro antimicrobial effi...
T70381 GSK2793660 free base
GSK-2793660 is a cathepsin C inhibitor that may be useful in the treatment of cystic fibrosis, noncystic fibrosis bronchiectasis, ANCA-associated vasculitis and bronchiectasis.
T11291 FKBP12 PROTAC dTAG-13 dTAG-13 Epigenetic Reader Domain
FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcription...
T71840 FKBP12-IN-Q2
FKBP12-IN-Q2 is an inhibitor of FKBP12.
T11292 FKBP12 PROTAC dTAG-7 dTAG-7 Epigenetic Reader Domain
FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional compound that selectively degrades the BET bromodomain transcriptional co-activator BRD4 by connecting BET bromodomains to the E3 ubiquitin ligase CRBN. Additionally,...
T13694 FKBP12 PROTAC RC32 RC32 Others
FKBP12 PROTAC RC32 contains conjugation of Rapamycin and a ligand for an E3 ubiquitin ligase.FKBP12 PROTAC RC32 (RC32) is a potent FKBP12 degrader based on PROTAC technology.
T79184 FKBP51F67V-selective antagonist Ligand2 FKBP
FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 or FKBP52 [1]. It effectively reverses the anxiogenic phenotype ...
T18610 PROTAC FKBP Degrader-3 Others
PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1].
T18597 DFKBP-1 Others
dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1].
T74144 Zifanocycline
Zifanocycline (KBP-7072), a third-generation semisynthetic aminomethylcycline antibiotic, inhibits bacterial ribosome function, displaying broad-spectrum antibacterial activity in vitro against both Gram-positive and Gra...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00589 KIAA1279 Protein, Human, Recombinant Human Baculovirus Insect Cells
KIAA1279 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 72 kDa and the accession number is Q96EK5.
TMPY-03993 KIAA1279 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
KIAA1279 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 99.6 kDa and the accession number is Q96EK5.
TMPY-03385 FKBP14 Protein, Human, Recombinant (His) Human HEK293 Cells
FKBP14 belongs to the FK506-binding protein family. It contains 2 EF-hand domains and one PPIase FKBP-type domain. FKBP14 can be detected in the lumen of the endoplasmic reticulum where it is thought to accelerate the fo...
TMPY-00510 FKBP11 Protein, Human, Recombinant (mFc) Human HEK293 Cells
FKBP11 serve as biomarker and/or therapeutic target for Acute aortic dissection (AAD). FKBP11 during the development of HCC and FKBP11 has the potential to be an early marker for HCC.
TMPY-02962 FKBP7 Protein, Human, Recombinant (hFc) Human HEK293 Cells
FKBP7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.4 kDa and the accession number is Q9Y680-2.
TMPY-02259 FKBP25/FKBP3 Protein, Human, Recombinant (GST) Human E. coli
FKBP3 is a member of FK506-binding proteins (FKBPs). miR-145-5p overexpression suppressed cell proliferation of NSCLC cells which was abrogated by FKBP3 overexpression, that FKBP3/Sp1/HDAC2/p27 control cell proliferation...
TMPJ-00919 FKBP2 Protein, Human, Recombinant (His) Human HEK293 Cells
Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It cont...
TMPJ-01076 FKBP4 Protein, Human, Recombinant (His) Human E. coli
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone recepto...
TMPY-03148 FKBP7 Protein, Human, Recombinant (His) Human HEK293 Cells
FKBP7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.8 kDa and the accession number is Q9Y680-2.
TMPY-00808 FKBP12 Protein, Human, Recombinant (His) Human E. coli
FKBP12 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.9 kDa and the accession number is P62942.
TMPJ-01068 FKBP25/FKBP3 Protein, Human, Recombinant (His) Human E. coli
FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell prolif...
TMPY-01662 FKBP12 Protein, Mouse, Recombinant (His) Mouse E. coli
FKBP12 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.7 kDa and the accession number is P26883.
TMPY-01555 PRAC Protein, Human, Recombinant (His & SUMO) Human E. coli
The PRAC gene is located on chromosome 17 at position 17q21, about 4 kbp downstream from the homeodomain Hoxb-13 gene. The pathogenesis of PCa may be due to the expression levels of PRAC protein, and this protein can ser...
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