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Search Results for " jak1-in-11 "

4

Compounds

Cat No. Product Name Synonyms Targets
T79079 JAK1-IN-11 JAK
JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations with IC50 values of 0.02 nM (JAK1) and 0.44 nM (JAK2), demonstrating high selectivity for JAK1 over J...
T1849 Momelotinib CYT11387,CYT387,LM-1149 Apoptosis , JAK , Autophagy
Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhib...
T2636 Decernotinib VX-509,VRT-831509 Tyrosine Kinases , JAK
Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
T61658 TYK2-IN-11
TYK2-IN-11 (Compound 5B) is a potent and selective inhibitor of Tyk-2, providing inhibition to TYK2-JH2 and JAK1-JH2 with IC50 values of 0.016 nM and 0.31 nM, respectively. This compound demonstrates potential for advanc...
TargetMol