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Search Results for " integrin "

20

Compounds

Cat No. Product Name Synonyms Targets
TP1484L α2β1 Integrin Ligand Peptide acetate α2β1 Integrin Ligand Peptide acetate (134580-64-6) Integrin
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor. α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the...
T13473 αvβ1 integrin-IN-1 Integrin
αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.
T36291 Integrin modulator 1
Integrin modulator 1 is a potent and selective α4β1 integrin agonist, with an IC50 of 9.8 nM for RGD-binding α4β1. Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin, with an EC50 of 12.9 nM[1]. Integ...
T40361 Integrin Binding Peptide
Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.
T40243 αvβ5 integrin-IN-1
αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2.
T15584 Integrin Antagonists 27 Others
Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.
T11663 Integrin-IN-2 Others
Integrin-IN-2 is an orally bioavailable pan αv integrin inhibitor.Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively.
TP1484 α2β1 Integrin Ligand Peptide
The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen recep...
T13473L αvβ1 integrin-IN-1 TFA (1689540-62-2 free base) αvβ1 integrin-IN-1 TFA Integrin
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).
TP1374 α2β1 Integrin Ligand Peptide TFA
α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a potential antagonist of the collagen receptor.
T79140 αvβ6 integrin inhibitor 2 Integrin
αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.
T82063 Integrin signaling inhibitor, mP13
Integrin Signaling Inhibitor mP13 is a compound that impedes both inside-out and outside-in integrin-mediated signaling processes, such as fibrinogen binding, platelet adhesion, and clot retraction [1].
T79792 αvβ1 integrin-IN-2 Integrin
αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. Additionally, this compound inhibits a range of other integrins, with IC50 valu...
T79918 α7β1 integrin modulator-1 Integrin
α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].
T63868 α5β1 integrin agonist-1
α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.
T12177 Natalizumab Integrin
Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.
T73625 αvβ1 integrin-IN-1 TFA
αvβ1 Integrin-IN-1 TFA (Compound C8) is a potent, selective inhibitor of αvβ1 integrin, demonstrating an IC 50 value of 0.63 nM. It exhibits antifibrotic effects [1].
T16695 Pyrintegrin Integrin
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...
T6812L Cyclo(-RGDfK) TFA Integrin
Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
TP1330 Cyclo(RADfK) Integrin
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD...
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