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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1186L | Ifenprodil | RC 61-91,RC-61-91,RC61-91,RC 6191 | Adrenergic Receptor , NMDAR |
Ifenprodil (RC61-91) is an inhibitor of the NMDA receptor, specifically of GluN1 (glycine-binding NMDA receptor subunit 1) and GluN2B (glutamate-binding NMDA receptor subunit 2) subunits. Additionally, Ifenprodil inhibit... | |||
T1186 | Ifenprodil Tartrate | Potassium Channel , NMDAR , iGluR | |
Ifenprodil is a selective NMDA receptor (glutamate) antagonist. | |||
T41182 | Ifenprodil hemitartrate | ||
Ifenprodil hemitartrate is a NMDA receptor antagonist, acting at the polyamine site. Also anα-adrenergic vasodilator.σ2ligand displaying about 3-fold selectivity overσ1sites. | |||
T11629 | Ifenprodil glucuronide | Others | |
Ifenprodil glucuronide, a derivative of Ifenprodil, is a vasodilator and an inhibitor of platelet aggregation. In contrast to Ifenprodil, Ifenprodil glucuronide does not affect platelet aggregation nor arterial contracti... | |||
T23457 | Threo Ifenprodil hemitartrate | Others | |
σ receptor agonist and NR2B subunit-selective NMDA receptor antagonist | |||
T8920 | Sepimostat | iGluR | |
Sepimostat exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat dimethanesulfonate inhibits the Ifenprodil binding with a Ki v... | |||
T22583 | Arcaine sulfate | NMDAR | |
Arcaine sulfate is a NMDA antagonist. | |||
T37096 | Sepimostat dimethanesulfonate | ||
Sepimostat dimethanesulfonate (FUT-187), a chemical compound, demonstrates neuroprotective properties by antagonizing NR2B N-methyl-D-aspartate receptors at the NR2B subunit's Ifenprodil-binding site. This compound effec... | |||
T71290 | EVT-101 HCl | ||
EVT-101 is a GluN2B antagonist, binding at the same GluN1/GluN2B dimer interface as ifenprodil but adopting a remarkably different binding mode involving a distinct subcavity and receptor interactions. | |||
T70049 | Ro 04-5595 free base | ||
Ro 04-5595 is a selective antagonist of NMDA receptors NR2B subunits. Ro 04-5595 had an EC 50 of 186 ± 32 nmol/L. Ro 04-5595 was predicted to bind the EVT-101 binding site, not the ifenprodil-binding site. Specific bindi... |