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Search Results for " hif-1α-in-4 "

4

Compounds

Cat No. Product Name Synonyms Targets
T60524 HIF--IN-4
HIF--IN-4 is an inhibitor of HIF- with IC50 of 24 nM in HEK293T cells which has potential antitumor effects. HIF--IN-4 downregulates VEGF and PDK1 mRNA expressions under hypoxia [1].
T79560 22-(4′-py)-JA 22-(4′-Pyridinecarbonyl) jorunnamycin A Akt
22-(4′-py)-JA, a semisynthetic derivative of junamycin A isolated from the Thai blue sponge (Xestospongia sp.), exhibits antimetastatic properties by inhibiting the AKT/mTOR/p70S6K signaling pathway. It also impedes tumo...
T68511 KRH102140
KRH102140 is a potent activator of PHD2. KRH102140, which has a structure similar to KRH102053. KRH102140 more efficiently suppressed HIF- than KRH102053 in human osteosarcoma cells under hypoxia. Furthermore, KRH10214...
T36749 Herboxidiene
Herboxidiene is a polyketide originally isolated from S. chromofuscus that has diverse biological activities.[1],[2,][3],[4],[5] It inhibits growth of HeLa S3, SK-MEL-2, PC3, A549, and EBC-1 cells with GI50 values rangin...
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