her2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2518	ARRY-380 (analog )	HER2-Inhibitor-1,ARRY380,ARRY-380 analog	EGFR , HER
	ARRY-380 analog (HER2-Inhibitor-1) is a potent and selective HER2 inhibitor.		EGFR , HER
TP1583L	HER2/neu (654-662) GP2 acetate		HER
	HER2/neu (654-662) GP2 acetate is derived from the human epidermal growth factor receptor 2 (HER2-Neu, 654–662). HER2/neu (654-662) GP2 acetate induces HLA-A2-restricted cytotoxic T lymphocytes reactive to various epithe...		HER
TP1583	HER2/neu (654-662) GP2
	Affibody (affibody) ligands that are specific for the extracellular domain of human epidermal growth factor receptor 2 (HER2/neu) have been selected by phage display technology from a combinatorial protein library based ...
T64003	HER2-IN-7
	HER2-IN-7 is a potent inhibitor of HER2. HER2-IN-7 has shown potential for the study of diseases associated with ErbBs, particularly HER2, including cancer.
T63881	HER2-IN-8
	HER2-IN-8 is an inhibitor of HER-2 that can be used in the study of cancer and inflammation-related diseases.
T63441	HER2-IN-6
	HER2-IN-6 is a potent inhibitor of HER2. HER2-IN-6 has the potential to be investigated in wild and/or mutant EGFR and/or HER2 kinase-mediated tumors.
T62271	HER2-IN-9
	HER2-IN-9 is an orally active HER2 inhibitor (IC50: 0.03 μM). HER2-IN-9 inhibits the proliferation and migration of HER-2-positive breast cancer cells and can be used in breast cancer research.
T60572	HER2-IN-10
	HER2-IN-10 is a psoralen derivative that induces apoptosis. HER2-IN-10 shows anti-breast cancer activity and light-activated cytotoxicity [1].
T60896	HER2-IN-11
	HER2-IN-11 is a psoralen derivative that induces apoptosis. HER2-IN-11 shows light-activated cytotoxicity and also exhibits anti-breast cancer activity [1].
T62487	HER2-IN-12
	HER2-IN-12 is an HER2 inhibitor with an IC50 value of 121 nM and can be used to study cancers such as breast cancer.
T75164	HER2-IN-13
	HER2-IN-13 (Compound 33) serves as an effective HER2 inhibitor, exhibiting an IC50 value of 8 nM, and additionally demonstrates inhibition of wt-EGFR with an IC50 of 0.40 μM [1].
T75165	HER2-IN-14
	HER2-IN-14 (Compound 34) is a potent inhibitor of HER2, achieving an inhibitory concentration (IC50) of 18 nM. Additionally, this compound exhibits inhibitory activity against wild-type EGFR (wt-EGFR) with an IC50 of 6.3...
T63432	HER2-IN-5
	HER2-IN-5 is an effective inhibitor of orally active HER-2.
T61732	EGFR/HER2-IN-6
	EGFR/HER2-IN-6 (compound 43) is a dual EGFR/HER2 and DHFR inhibitor with potent activity against EGFR kinase, HER2 kinase, and DHFR, characterized by IC50 values of 0.122 μM, 0.078 μM, and 0.585 μM, respectively. This co...
T62776	EGFR/HER2-IN-2
	EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual EGFR and HER2 inhibitor that acts on both EGFR (IC50: 5.02 μM) and HER2 (IC50: 0.83 μM).
T60938	EGFR/HER2-IN-8
	EGFR/HER2-IN-8 (compound 34) is an inhibitor of EGFR/HER2 and DHFR with IC50 values of 0.45, 0.244 and 5.669 μM for EGFR, HER2 and DHFR, respectively. EGFR/HER2-IN-8 can be used in the cancer research that exhibits antic...
T61272	EGFR/HER2-IN-7
	EGFR/HER2-IN-7 is a highly selective and potent anticancer compound specifically designed to target MCF-7 breast cancer cells. It functions as a dual inhibitor, targeting both EGFR/HER2 kinases and DHFR (dihydrofolate re...
T62777	EGFR/HER2-IN-3
	EGFR/HER2-IN-3 (Compound ZINC21942954) is a dual EGFR and HER2 inhibitor.
T72854	EGFR/HER2-IN-9
	EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFR T790M mutation.
T64253	EGFR/HER2-IN-4
	EGFR/HER2-IN-4 is an irreversible, orally active dual inhibitor of EGFR activity (IC50: 0.6 nM). EGFR/HER2-IN-4 shows potent EGFR kinase inhibitory activity against L858R and T790M mutations. EGFR/HER2-IN-4 exhibits sign...