3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63416 | HDAC-IN-39 | ||
HDAC-IN-39 is a potent inhibitor of HDAC and is able to act on HDAC1, HDAC2 and HDAC3 with IC50 values of 1.07 μM, 1.47 μM and 2.27 μM, respectively. HDAC-IN-39 induces cell cycle arrest in G2/M phase and also significan... | |||
T2078 | Fimepinostat | CUDC-907,PI3K/HDAC Inhibitor,CUDC 907 | Apoptosis , PI3K , HDAC |
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, C... | |||
T36629 | Givinostat | ||
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF30... |