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Search Results for " gzmb "

Targets

2

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T72626 A2AR-antagonist-1 Adenosine Receptor
A2AR-antagonist-1 (compound 38), an orally active adenosine A2A receptor antagonist with an IC50 value of 29 nM, demonstrates anti-tumor properties and stability in mouse liver microsomes (t1/2 = 86.1 min). Additionally,...
T71890 F5446
F5446 is a SUV39H1 inhibitor. F5446 has an EC50 of 0.496 μmol/L for SUV39H1 enzymatic activity. H3K9me3 was enriched in the promoters of GZMB, PRF1, FASLG, and IFNG in quiescent T cells. F5446 inhibited H3K9me3, thereby ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00817 Granzyme B/GZMB Protein, Human, Recombinant (His) Human HEK293
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPJ-00770 Granzyme B/GZMB Protein, Mouse, Recombinant (His) Mouse Human Cells
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an...
TMPY-00818 Granzyme H/GZMH Protein, Human, Recombinant (His) Human HEK293
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes...
TMPH-01057 Caspase-8 Protein, Human, Recombinant (His) Human E. coli
Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood...
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