5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12192 | NCGC00229600 | Others , TSH Receptor | |
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies. | |||
T0952 | Carbimazole | Athyromazole,Carbimazol,Neomercazole | Thyroid hormone receptor(THR) |
Carbimazole (Athyromazole) is an Imidazolium thyroid antagonist, which is rapidly transformed into MMI in vivo and can be converted into methidazole in vitro, and can be used in the study of Graves' disease. | |||
T16106 | ML224 | NCGC00242364,ANTAG3 | TSH Receptor |
ML224 (NCGC00242364) is a TSHR antagonist for the treatment of Graves' orbital disease and Graves' hyperthyroidism. | |||
T13217 | TSHR antagonist S37a | Others | |
TSHR antagonist S37a is a selective antagonist of thyrotropin receptor (TSHR), with potential for the treatment of Graves' orbitopathy. | |||
T77043 | Iscalimab | ||
Iscalimab (CFZ-533), a non-depleting IgG1 monoclonal antibody that targets CD40 with a dissociation constant (K D) of 0.3 nM, is utilized in the research of Graves' hyperthyroidism and autoimmune diseases [1] [2] [3]. |