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5

Compounds

Cat No. Product Name Synonyms Targets
T12192 NCGC00229600 Others , TSH Receptor
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.
T0952 Carbimazole Athyromazole,Carbimazol,Neomercazole Thyroid hormone receptor(THR)
Carbimazole (Athyromazole) is an Imidazolium thyroid antagonist, which is rapidly transformed into MMI in vivo and can be converted into methidazole in vitro, and can be used in the study of Graves' disease.
T16106 ML224 NCGC00242364,ANTAG3 TSH Receptor
ML224 (NCGC00242364) is a TSHR antagonist for the treatment of Graves' orbital disease and Graves' hyperthyroidism.
T13217 TSHR antagonist S37a Others
TSHR antagonist S37a is a selective antagonist of thyrotropin receptor (TSHR), with potential for the treatment of Graves' orbitopathy.
T77043 Iscalimab
Iscalimab (CFZ-533), a non-depleting IgG1 monoclonal antibody that targets CD40 with a dissociation constant (K D) of 0.3 nM, is utilized in the research of Graves' hyperthyroidism and autoimmune diseases [1] [2] [3].
TargetMol