Powder: -20°C for 3 years
In solvent: -80°C for 6 months
ML224 is a selective TSHR inverse agonist. ML224 also inhibits TSH-stimulated cAMP production (IC50 = 2.3 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | Inquiry | 88.00 | |
5 mg | Inquiry | 126.00 | |
10 mg | Inquiry | 198.00 | |
50 mg | Inquiry | 612.00 | |
100 mg | Inquiry | 976.00 |
Description | ML224 is a selective TSHR inverse agonist. ML224 also inhibits TSH-stimulated cAMP production (IC50 = 2.3 μM). |
Targets&IC50 | Others |
In vivo | ANTAG3 lowered serum-free T4 by 44% and lowered mRNAs for sodium-iodide cotransporter and thyroperoxidase by 75% and 83%, respectively, in mice treated with TRH. ANTAG3 lowered serum-free T4 by 38% and lowered mRNAs for sodium-iodide cotransporter and thyroperoxidase by 73% and 40%, respectively, in mice given M22 [2]. |
Synonyms | NCGC00242364 , ANTAG3 |
Purity | |
Molecular Weight | 525.59 |
Formula | C31H31N3O5 |
CAS No. | 1338824-21-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 6 months
DMSO: 100 mg/mL (190.26 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.