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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2146 | Fulvestrant | ZM 182780,ZD 9238,ICI 182780 | Apoptosis , Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Autophagy |
Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30. Fulvestrant has antitumor activity, inhibiting cell proliferation and inducing apoptosis and autophagy. | |||
T11335 | Fulvestrant (S enantiomer) | ZM 182780 S enantiomer,ICI 182780 S enantiomer,Fulvestrant S enantiomer,ZD 9238 S enantiomer | Others |
Fulvestrant S enantiomer is the less active S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM. | |||
T11334 | Fulvestrant (R enantiomer) | ICI 182780 R enantiomer,ZD 9238 R enantiomer,ZM 182780 R enantiomer,Fulvestrant R enantiomer | Others |
Fulvestrant R enantiomer is the less active R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM. | |||
T71710 | Fulvestrant sulfone | ||
Fulvestrant sulfone is a synthetic estrogen receptor antagonist. | |||
T82366 | Fulvestrant 3-β-D-Glucuronide | ||
Fulvestrant 3-β-D-Glucuronide, a glucuronide and sulfate conjugate metabolite of the pure anti-estrogenic steroid Fulvestrant, is utilized in breast cancer research [1]. | |||
T71578 | Endoxifen mesylate | ||
Endoxifen, also known as N-desmethyl-4-hydroxytamoxifen, is a chemical that is under development for estrogen receptor-positive breast cancer. It is also being evaluated as an antipsychotic for treatment of mania and ot... |