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Search Results for " fcγr "

7

Compounds

Cat No. Product Name Synonyms Targets
T9192 BIIB068 BTK
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
T76735 Mupadolimab CPI-006 CD73
Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells.
T81449 PKC-ε translocation inhibitor peptide PKC
PKC-ε Translocation Inhibitor Peptide is a selective modulator that controls the FcγR-mediated internalization rate of opsonized beads without affecting FcαR trafficking [1].
T80880 Valziflocept BAX1810,TAK-752
Valziflocept (BAX1810; TAK-752) is a recombinant soluble human FcγRIIb receptor designed to act as a "decoy" or "scavenger" by targeting Fc and FcγR, binding and neutralizing pathogenic IgG. Its utility lies in mitigatin...
T77090 Mitazalimab
Mitazalimab (ADC-1013; JNJ-64457107) is an FcγR-dependent CD40 agonist that exhibits directed activity against tumors. By activating antigen-presenting cells, such as dendritic cells (DC), it triggers the initiation of t...
T81968 KY-1044 SAR 445256,Alomfilimab
KY-1044 (Alomfilimab; SAR 445256) is a fully human IgG1 monoclonal antibody that targets the inducible costimulatory receptor (ICOS). This compound selectively depletes cells with high ICOS expression through antibody-de...
T63254 BTK-IN-11
BTK-IN-11 is a potent inhibitor of BTK. BTK-IN-11 has shown potential for research in diseases related to autoimmune diseases, inflammatory diseases or cancer.
TargetMol