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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79420 | FLT3-IN-22 | ||
FLT3-IN-22 (compound 22f) is a potent inhibitor of FLT3, demonstrating IC50 values of 0.941 nM for FLT3 and 0.199 nM for the FLT3/D835Y mutant. This compound displays significant antiproliferative effects against MV4-11 ... | |||
T6020 | Pacritinib | SB1518 | FLT , Tyrosine Kinases , JAK |
Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays). | |||
T3211 | Midostaurin | N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 | Others , PKC |
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel... | |||
T64283 | Pacritinib hydrochloride | ||
Pacritinib hydrochloride is a potent inhibitor of wild-type JAK2 (IC50: 23 nM) and the JAK2V617F mutant (IC50: 19 nM). Pacritinib hydrochloride can be used in the study of acute myeloid leukaemia (AML) and myelofibrosis ... |