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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21954 | EGFR/ErbB-2/ErbB-4 inhibitor-2 | EGFR/ErbB2 Inhibitor | EGFR |
EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively) | |||
T5410 | PD158780 | EGFR | |
PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR, ErbB2, ErbB3, and ErbB4 (IC50s: 8μM, 49 nM, 52 nM, and 52 nM in cell assay). | |||
T2483 | Dacomitinib | PF-299804,PF-00299804,PF299 | Apoptosis , EGFR |
Dacomitinib (PF299)(PF299804; PF-00299804) is a highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2, and ERBB4, respective... | |||
T2491 | AZ-5104 | EGFR | |
AZ5104 is a potent EGFR inhibitor. | |||
T6331 | Allitinib tosylate | AST-1306 TsOH,AST-6,Allitinib,AST-1306,AST-1306 (TsOH) | EGFR , FLT |
Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively. | |||
T14336 | Allitinib | AST-1306,ALS 1306 | EGFR |
Allitinib (AST-1306) (AST-1306) has anti-cancer activity,and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1] |