5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8551 | Nitrobenzylthioinosine | NBMPR | AChR , Adenosine Receptor |
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity. | |||
T75026 | PROTAC TYK2 degradation agent1 | PROTACs | |
PROTAC TYK2 Degradation Agent1 is a potent, subtype-selective degrader of TYK2, exhibiting degradation activity with a DC50 of 14 nM. It is utilized in autoimmune disease research [1]. | |||
T10212 | A2AR-agonist-1 | N-(2-(1H-Indol-3-yl)ethyl)adenosine | Others , Adenosine Receptor |
A2AR-agonist-1 (N-(2-(1H-Indol-3-yl)ethyl)adenosine) is a potent A2AR and ENT1 agonist (Ki: 4.39 and 3.47 for A2AR and ENT1. It targets the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection. | |||
T37804 | 8MDP | ||
Potent equilibrative nucleoside transporter 1 (ENT1) inhibitor (IC50 = 0.43 nM). Inhibits hENT1 and hENT2 uptake of [H3]uridine in K562 cells and K15NTD cells respectively. Lin et al (2011) Design, synthesis, and evaluat... | |||
T15167 | Draflazine | R-75231 | Others |
Draflazine is an ENT1 inhibitor. It completely reverses the hypersensitivity in the complete Freund’s adjuvant (CFA) model of mechanical hyperalgesia. Draflazine also completely reverses the hypersensitivity of the carra... |