enpp1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T37431	ENPP1 Inhibitor C	ENPP1 Inhibitor C
	ENPP1 inhibitor C is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50 = 0.26 μM in a cell-free assay).1 It is selective for ENPP1 over ENPP2-7 at 10 μM. ENPP1 inhibitor C decreases ENPP1 ac...
T69560	ENPP1 inhibitor 43
	ENPP1 inhibitor 43 is a novel small molecule for cancer immunotherapy.
T78169	Enpp-1-IN-16		PDE
	Enpp-1-IN-16 is an inhibitor targeting ENPP1 with potential anti-cancer activity.Enpp-1-IN-16 can be used to study insulin resistance in relation to type II diabetes mellitus and various ENPP1-mediated diseases in the ch...		PDE
T60105	Enpp-1-IN-14		PDE
	Enpp-1-IN-14 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. Enpp-1-IN-14 has anti-tumor activity.		PDE
T36133	3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)
	3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) is a non-nucleotide inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; Ki = 50 μM).1,2 It also inhibits urease (IC50 = 84.53 μM for the...
T61514	Enpp-1-IN-12
	Enpp-1-IN-12 (compound 43), an orally active and potent inhibitor of ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1) with a K i of 41 nM, exhibits anti-tumor activity [1].
T60669	Enpp-1-IN-10
	Enpp-1-IN-10 (compound 1) is a potent inhibitor of Ecto-nucleotide pyrophosphatase/phosphodiesterases 1(ENPP1) with an Ki value of 3.866 μM that can be used in anticancer research [1].
T63535	Enpp-1-IN-13
	Enpp-1-IN-13 is an ectonucleotide pyrophosphatase/phosphodiesterase (ENPP) inhibitor that is able to act on ENPP1 (IC50: 1.29 μM) and ENPP3 (IC50: 20.2 μM), exhibiting anticancer effects.
T37832	CAY10761	CAY10761
	CAY10761 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50s = 467 and 429 μM for the human and snake venom enzymes, respectively).1,2 It also inhibits mushroom tyrosinase (Ki = 1.9 μM) an...
T79032	Enpp-1-IN-17
	Enpp-1-IN-17 (example 274) is a potent inhibitor of ENPP1, exhibiting inhibition constants (Ki values) of 100 nM-1 μM for cGAMP hydrolysis and >1 μM for ATP hydrolysis, respectively, with a selectivity ratio of >6.4 favo...
T61136	Enpp-1-IN-11
	Enpp-1-IN-11 (compound 23) is a highly potent inhibitor of Ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1), with a Ki value of 45 nM. It demonstrates excellent stability in human and mouse plasma and exhibit...
T61860	Enpp-1-IN-9
	Enpp-1-IN-9, a powerful inhibitor of ectonucleotide pyrophosphatase-phosphodiesterase 1 (ENPP1), exhibits wide substrate specificity, capable of cleaving various bonds such as phosphodiester bonds of nucleotides and nucl...

Compounds

ENPP1 Inhibitor C

T37431

Synonym: ENPP1 Inhibitor C

3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)

Recombinant Proteins

Species：

Expression System：

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Cat No.	Product Name	Species	Expression System
TMPK-00781	ENPP1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP...
TMPK-00854	ENPP1 Protein, Human, Recombinant (C-His)	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP...
TMPK-00853	ENPP1 Protein, Human, Recombinant (N-His)	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP...
TMPK-00852	ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP...