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Search Results for " eif4g "

Targets

4

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T14044 4E2RCat PERK
4E2RCat is an eIF4E-eIF4G interaction inhibitor (IC50: 13.5 μM).
T1742 4E1rcat PERK , Autophagy
4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.
T2665 4EGI-1 4EGI 1 Apoptosis , PERK , Autophagy
4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).
T37099 (Z)-4EGI-1
(Z)-4EGI-1, the Z-isomer of 4EGI-1, serves as an inhibitor of both the eIF4E/eIF4G interaction and translation initiation. It effectively binds to eIF4E, exhibiting an IC50 of 43.5 μM and a Kd value of 8.74 μM. Notably, ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01312 EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc) Human E. coli
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-01313 EIF4G1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPY-01769 4EBP1 Protein, Human, Recombinant (His) Human E. coli
The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcrip...
TMPY-06821 THRB Protein, Human, Recombinant (His) Human E. coli
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin...
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