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Search Results for " dll4 "

Targets

4

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T76788 Demcizumab OMP 21M18 Gamma-secretase
Demcizumab (OMP 21M18) is an anti-DLL4 monoclonal antibody. Demcizumab is a potent Notch pathway inhibitor. Demcizumab is effective in multiple cancer models, both alone and in combination with chemotherapy agents.
T77157 Dilpacimab
Dilpacimab (ABT165), a potent dual-variable domain immunoglobulin, targets both the delta-like ligand 4 (DLL4) and VEGF pathways. It has potential applications in cancer research [1].
T76871 Navicixizumab
Navicixizumab (OMP-305B83) is a bispecific anti- VEGF and anti- DLL4 inhibitory antibody. Navicixizumab can combine with Paclitaxel for cancer research. Navicixizumab can be used in the research of ovarian, primary peri...
T80615 Enoticumab REGN421
Enoticumab (REGN421, SAR153192) is an IgG1κ antibody that specifically targets human Delta-like ligand 4 (Dll4), which serves as a crucial component of the Notch signaling pathway and regulates the uptake of fatty acids ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01337 DLL4 Protein, Mouse, Recombinant (His) Mouse HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-01321 DLL4 Protein, Human, Recombinant (His) Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-04803 DLL4 Protein, Human, Recombinant Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-00776 DLL4 Protein, Human, Recombinant (hFc) Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPK-00360 DLL4 Protein, Human, Recombinant (His & Avi) Human HEK293
Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell pro...
TMPY-05796 DLL4 Protein, Mouse, Recombinant (mFc) Mouse HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-05093 DLL4 Protein, Rhesus, Recombinant (His) Rhesus HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-06876 DLL4 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPH-00879 ASCL1 Protein, Human, Recombinant (His) Human E. coli
Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. Directly binds the E...
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