5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5969 | Ditolylguanidine | DTG,Di-o-tolylguanidine,1,3-Di-o-tolylguanidine | Sigma receptor |
Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor). | |||
T13510 | Sigma-LIGAND-1 | Sigma receptor | |
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor. | |||
T62396 | KB-5492 free base | ||
KB-5492 free base is a potent and selective sigma receptor inhibitor, inhibiting [3H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC50 value of 3.15 μM. KB-5492 free base is an anti-ulcer agent. | |||
T2329 | Dolutegravir sodium | GSK1349572,GSK-1349572A | HIV Protease |
Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. | |||
T63048 | Sigma-LIGAND-1 hydrochloride | ||
Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand that acts at the DTG (IC50: 16 nM) and PPP (IC50: 19 nM) sites. Sigma-LIGAND-1 hydrochloride is able to act on the dopamine D2 receptor (Ki: 4000 nM). |