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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63647 | DCN1-UBC12-IN-1 | ||
DCN1-UBC12-IN-1 is a potent and specific DCN1-UBC12 inhibitor with an IC50 value of 2.86 nM and anti-cardiac fibrogenic activity. | |||
T63820 | DCN1-UBC12-IN-2 | ||
DCN1-UBC12-IN-2 is a potent, specific DCN1-UBC12 inhibitor with an IC50 value of 9.55 nM. DCN1-UBC12-IN-2 specifically targets DCN1-UBC12 interactions and slows Ang II-induced activation of cardiac fibroblasts. | |||
T13349 | WS-383 | E1/E2/E3 Enzyme | |
WS-383 is a selective, potent and reversible DCN1-UBC12 interaction inhibitor(IC50 of 11 nM). | |||
T9140 | NAcM-OPT HCl(2089293-61-6 free base) | NEDD8 | |
NAcM-OPT HCL is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor that targets N-Acetyl-UBE2M (E2 conjugating enzyme, UBC12) interaction with DCN1 with IC50 of 79 nM. | |||
T13348 | WS-383 free base | Others | |
WS-383 free base is a selective and reversible DCN1-UBC12 interaction inhibitor(IC50 of 11 nM). | |||
T23989 | DI-404 | ||
DI-404 is a high-Affinity Peptidomimetic the DCN1-UBC12 Protein-Protein Interaction inhibitor (Kd= 6.9 nM). DI-404 effectively and selectively inhibits the neddylation of cullin 3 over other cullin members. | |||
T11033 | DI-591 | Others | |
DI-591 is an effective, high-affinity and cell-permeability inhibitor for DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 and nM and 10.4 nM, respectively, and has no obvious binding to DCN3, D... |