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Search Results for " dbc "

20

Compounds

Cat No. Product Name Synonyms Targets
T20907 DBC 3,4,5,6-Dibenzocarbazole
DBC, a ubiquitous environmental pollutant, induces significant DNA strand break levels and micronuclei in HepG2 cells.
T20214 Bucladesine Bucladesina,DT 5621,DBC-AMP,Actosin
Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is capable of permeating the cell membrane. Bucladesine is a phosphodiesterase inhibitor. The compound is used in a wide variet...
T15069 DBCO-PEG4-Biotin ADIBO-NH-PEG2-Biotin Others
DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into ...
T15076 DBCO-S-S-PEG3-biotin Others , PROTAC Linker
DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved using reducing agents s...
T15058 DBCO-amine
DBCO-amine is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis[1].
T15067 DBCO-NHS ester Others
DBCO-NHS ester is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).
T9282 DBCO-C3-Acid DBCO-ACID Others
DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates.
T17791 DBCO-PEG3-NHS ester Others
DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.
T17753 DBCO-mPEG (MW 5kDa) Others
DBCO-mPEG (MW 5kDa) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst...
T15073 DBCO-PEG4-NHS ester PROTAC Linker
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
T17451 APN-PEG4-DBCO Others
APN-PEG4-DBCO is a cleavable linker for antibody-drug conjugates (ADCs), comprised of a four-unit PEG and a DBCO moiety. It finds application in the synthesis of ADCs[1].
T17811 DBCO-SS-aldehyde Others
DBCO-SS-aldehyde is an ADC linker employed for ADC synthesis[1]. This cleavable linker is designed to facilitate the conjugation of antibodies and drugs, resulting in antibody-drug conjugates (ADCs).
T15062 DBCO-NHCO-PEG4-amine Others
DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)[1].
T16056 Methyltetrazine-DBCO Others
Methyltetrazine-DBCO is a non-cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
T18969 DBCO-Cy3 DBCO-Sulfo-Cy3 Others
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dye (excitation maximum: 555 nm; emission maximum: 580 nm).
T39897 DBCO-PEG4-MMAF DBCO-PEG4-MMAF
DBCO-PEG4-MMAF is an antibody-drug conjugate (ADC) component that exhibits potent antitumor activity. It combines the tubulin polymerization inhibitor MMAF with a cleavable linker, DBCO-PEG4, to target cancer cells effec...
T17802 DBCO-PEG4-VC-PAB-DMEA-PNU-159682 Others
DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for antibody-drug conjugates (ADC), comprises the ADC linker DBCO-PEG4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682. The cytotoxin includes metabolites of ...
T15074 DBCO-PEG4-TAMRA Others
DBCO-PEG4-TAMRA, contains a DBCO group, is a PEG-based TARMA dye. The TAMRA dye is a dye widely used in oligonucleotide labeling.
T17764 DBCO-NHCO-PEG2-Biotin Others
DBCO-NHCO-PEG2-Biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sy...
T15085 Dde Biotin-PEG4-DBCO Others
Dde Biotin-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys...
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