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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20907 | DBC | 3,4,5,6-Dibenzocarbazole | |
DBC, a ubiquitous environmental pollutant, induces significant DNA strand break levels and micronuclei in HepG2 cells. | |||
T20214 | Bucladesine | Bucladesina,DT 5621,DBC-AMP,Actosin | |
Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is capable of permeating the cell membrane. Bucladesine is a phosphodiesterase inhibitor. The compound is used in a wide variet... | |||
T15069 | DBCO-PEG4-Biotin | ADIBO-NH-PEG2-Biotin | Others |
DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into ... | |||
T15076 | DBCO-S-S-PEG3-biotin | Others , PROTAC Linker | |
DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved using reducing agents s... | |||
T15058 | DBCO-amine | ||
DBCO-amine is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis[1]. | |||
T15067 | DBCO-NHS ester | Others | |
DBCO-NHS ester is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs). | |||
T9282 | DBCO-C3-Acid | DBCO-ACID | Others |
DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates. | |||
T17791 | DBCO-PEG3-NHS ester | Others | |
DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules. | |||
T17753 | DBCO-mPEG (MW 5kDa) | Others | |
DBCO-mPEG (MW 5kDa) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst... | |||
T15073 | DBCO-PEG4-NHS ester | PROTAC Linker | |
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1]. | |||
T17451 | APN-PEG4-DBCO | Others | |
APN-PEG4-DBCO is a cleavable linker for antibody-drug conjugates (ADCs), comprised of a four-unit PEG and a DBCO moiety. It finds application in the synthesis of ADCs[1]. | |||
T17811 | DBCO-SS-aldehyde | Others | |
DBCO-SS-aldehyde is an ADC linker employed for ADC synthesis[1]. This cleavable linker is designed to facilitate the conjugation of antibodies and drugs, resulting in antibody-drug conjugates (ADCs). | |||
T15062 | DBCO-NHCO-PEG4-amine | Others | |
DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)[1]. | |||
T16056 | Methyltetrazine-DBCO | Others | |
Methyltetrazine-DBCO is a non-cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T18969 | DBCO-Cy3 | DBCO-Sulfo-Cy3 | Others |
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dye (excitation maximum: 555 nm; emission maximum: 580 nm). | |||
T39897 | DBCO-PEG4-MMAF | DBCO-PEG4-MMAF | |
DBCO-PEG4-MMAF is an antibody-drug conjugate (ADC) component that exhibits potent antitumor activity. It combines the tubulin polymerization inhibitor MMAF with a cleavable linker, DBCO-PEG4, to target cancer cells effec... | |||
T17802 | DBCO-PEG4-VC-PAB-DMEA-PNU-159682 | Others | |
DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for antibody-drug conjugates (ADC), comprises the ADC linker DBCO-PEG4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682. The cytotoxin includes metabolites of ... | |||
T15074 | DBCO-PEG4-TAMRA | Others | |
DBCO-PEG4-TAMRA, contains a DBCO group, is a PEG-based TARMA dye. The TAMRA dye is a dye widely used in oligonucleotide labeling. | |||
T17764 | DBCO-NHCO-PEG2-Biotin | Others | |
DBCO-NHCO-PEG2-Biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sy... | |||
T15085 | Dde Biotin-PEG4-DBCO | Others | |
Dde Biotin-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... |