store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DBCO-mPEG (MW 5kDa) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 64.00 | |
25 mg | In stock | $ 97.00 |
Description | DBCO-mPEG (MW 5kDa) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, consisting of two distinct ligands joined by a linker, feature one ligand that binds to an E3 ubiquitin ligase, and the other ligand that targets a specific protein of interest. These molecules harness the intracellular ubiquitin-proteasome system to achieve the selective degradation of the target proteins.[1] |
Molecular Weight | 5kDa |
CAS No. | T17753 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL
You can also refer to dose conversion for different animals. More
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