cdk2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1875	CDK2
	CDK2, a eukaryotic S/T protein kinase family member, catalyzes the phosphoryl transfer from ATP γ-phosphate to the hydroxyl of serine or threonine (denoted as S0/T0) in a protein substrate.
T36933	Cdk2 Inhibitor II	Cdk2 Inhibitor II,CDK2-IN-3	CDK
	Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.		CDK
T14916	CDK2-IN-4		CDK
	CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A. It shows 2,000-fold selectivity over CDK1/cyclin B with IC50 of 86 uM.		CDK
TP1875L	CDK2 acetate(255064-79-0 free base)		Others
	CDK2 acetate is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate.		Others
T40160	CDK2-IN-7	CDK2-IN-7
	CDK2-IN-7 is a CDK2 inhibitor for treating cancer ( IC 50 < 50 nM).
T35555	GSK-3/CDK5/CDK2-IN-1	GSK-3/CDK5/CDK2-IN-1
	GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].
T3195	CVT-313	CVT 313,Cdk2 Inhibitor III,CVT313,NG26	CDK
	CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.		CDK
T60154	CDK2-IN-13
	CDK2-IN-13 is a potent Cyclin-dependent kinase 2 (CDK2) inhibitor (IC50 value: 12 µM).CDK2-IN-13 is involved in cell cycle regulation and can arrest the cell cycle. CDK2-IN-13 prevents cell division and proliferation, in...
TP2192	Cdk2/Cyclin Inhibitory Peptide I		Others
	Cyclin-dependent kinase 2 also known as cell division protein kinase 2. The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases. This protein kinase is highly similar...		Others
T12552	PROTAC CDK2/9 Degrader-1		CDK
	PROTAC CDK2/9 Degrader-1 is a potent CDK2 and CDK9 dual degrader(DC50 of 62 nM and 33 nM).		CDK
T62038	CDK2-IN-8
	CDK2-IN-8 is a potent CDK2 inhibitor (IC50= 1.74 μM). CDK2-IN-8 exhibits antiproliferative activity. CDK2-IN-8 can be used for the research of melanoma.
T62668	CDK2-IN-12
	CDK2-IN-12 (compound 10b) is a potent inhibitor of CDK2 (IC50: 11.6 μM). CDK2-IN-12 exhibits inhibition of hCA subtypes I, II, IX and XII with KI values of 3534, 638.4, 44.3 and 48.8 nM, respectively. CDK2-IN-12 shows CD...
T82759	CDK2-IN-20		CDK
	CDK2-IN-20 (compound 3b), a CDK2 inhibitor, exhibits cytotoxic effects on tumor cells with an IC50 ranging from 5.52-17.09 µM. It arrests the MCF-7 cell cycle at the S phase and induces apoptosis [1].		CDK
T79729	EGFR/CDK2-IN-4		EGFR
	EGFR/CDK2-IN-4 (compound 4c) is a dual inhibitor targeting EGFR and CDK-2, demonstrating IC50 values of 89.6 nM for EGFR and 165.4 nM for CDK-2. It prompts apoptosis in MCF-7 cells and causes S phase cell cycle arrest, e...		EGFR
T62567	CDK2-IN-9
	CDK2-IN-9 is a potent inhibitor of CDK2 (IC50: 0.63 μM) with anti-proliferative effects. CDK2-IN-9 is capable of blocking the cell cycle in S and G2/M phases and inducing apoptosis. CDK2-IN-9 has potential for melanoma r...
T62337	CDK2-IN-11
	CDK2-IN-11 (compound 9d) is a potent inhibitor of CDK2 (IC50: 6.4 μM) and acts on hCA II (Ki: 23.4 nM), hCA IX (Ki: 56.3 nM) and hCA XII (Ki: 44.3 nM). CDK2-IN-11 can be used in anticancer studies.
T79648	CDK2-IN-19		CDK
	CDK2-IN-19 (Compound 32) is a selective, orally active inhibitor of CDK2 (K i: 0.18 nM) that exhibits anticancer activity in mice with OVCAR3 tumors [1].		CDK
T79727	EGFR/CDK2-IN-2		EGFR
	EGFR/CDK2-IN-2 (compound 6a) serves as a dual inhibitor targeting both EGFR and CDK-2, exhibiting IC50 values of 19.6 nM and 87.9 nM, respectively. It promotes apoptosis in MCF-7 cells and halts cell cycle progression du...		EGFR
T76377	Cdk2/Cyclin Inhibitory Peptide II
	Cdk2/Cyclin Inhibitory Peptide II (Tat-LDL), a CDK2 inhibitor, demonstrates dose-dependent cytotoxic effects on U2OS osteosarcoma cells [1].
T72844	EGFR/CDK2-IN-1
	EGFR/CDK2-IN-1, an inhibitor of both EGFR and CDK2, demonstrates effective cytotoxicity towards MCF7 and HepG2 cells, suggesting its potential application in cancer research.