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Search Results for " cdc20 "

8

Compounds

Cat No. Product Name Synonyms Targets
T4647 M2I-1 M2I 1 Others
M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 cri...
T8561 Apcin APC
Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substr...
T64339 Apcin A HCL APC
Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to...
T1731 TAME hydrochloride Tos-Arg-OMe HCl,TOS-ARG-OME hydrochloride Amino Acids and Derivatives , APC
TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.
T10345 Apcin-A Others
Apcin-A is an anaphase-promoting complex (APC) inhibitor. It interacts strongly with Cdc20 and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.
T14642 Bis-PEG5-acid PROTAC Linker 36 Others
Bis-PEG5-acid (PROTAC Linker 36) is a polyethylene glycol (PEG) linker employed for the synthesis of CP5V, a PROTAC that selectively degrades Cdc20[1].
T10875 CP5V Others
CP5V, a PROTAC, induces mitotic inhibition, and suppresses cancer cell proliferation. It specifically degrades Cdc20 by linking Cdc20 to the VHL/VBC complex for ubiquitination followed by proteasomal degradation.
T6693 TAME Tosylarginine methyl ester,N-4-Tosyl-L-arginine methyl ester APC
Tosyl-L-Arginine Methyl Ester (TAME (N-4-Tosyl-L-arginine methyl ester)) is an APC inhibitor.
TargetMol