5
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4577 | Cariprazine | RGH-188 | Dopamine Receptor , 5-HT Receptor |
Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). | |||
T8382 | Cariprazine hydrochloride | Cariprazine HCl,RGH188 hydrochloride | Dopamine Receptor , 5-HT Receptor |
Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively) | |||
T15117 | Didesmethyl cariprazine | Dopamine Receptor , 5-HT Receptor | |
Didesmethyl cariprazine, a metabolite of Cariprazine, is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is a potent D3 preference D3/D2 receptor partial agonist of do... | |||
T15100 | Desmethyl cariprazine | Dopamine Receptor , 5-HT Receptor | |
Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A... | |||
T10681 | Cariprazine D6 | RGH-188 D6 | Dopamine Receptor |
Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM). |