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Search Results for " cyslt1 "

Targets

16

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T11388 Gemilukast ONO-6950 Others
Gemilukast (ONO-6950) is an orally active and potent dual inhibitor of cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2), inhibits LTC 4-induced bronchoconstriction, and is inhibitory to human CysLT1 and CysLT2...
T7841 MK 571 L660711,L-660711,MK-571 LTR
MK 571 (L660711) is an orally active antagonist of CysLT1 receptor.
T3148 MK-571 sodium L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid Leukotriene Receptor , LTR
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the ...
T22668 Cinalukast Others
CysLT1 leukotriene receptor antagonist
T71273 CAY10788
CAY10788 is an antagonist of CysLT1 receptor.
T69278 FPL-55712
FPL-55712 is a CysLT1 leukotriene receptor antagonist.
T11860 LM-1484 Others
LM-1484 displays a higher affinity for 3H-LTC4 sites and is an antagonist of CysLT1 receptor.
T70330 ONO-2050297
ONO-2050297 is the first potent dual CysLT1 and CysLT2 antagonist with IC50 values of 0.017 μM (CysLT1) and 0.00087 μM (CysLT2), respectively.
T68392 ONO-4310321
ONO-4310321 is a potent, orally available dual CysLT1 and CysLT2 receptor antagonist.
T37016 Iralukast (CGP 45715A)
Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.
T31043 CP-199330 UNII-V4WYK6T8QA,CP 199330,UNII-74573Q728X,CP-199330 sodium
CP-199330 is a cysteyl LT1 receptor antagonist with no hepatotoxicity and is equivalent to the commercially available CYSLT1 receptor antagonists Zafirlukast and Pranlukas.
T37386 Dihydro Montelukast
Dihydro montelukast is a potential impurity found in commercial montelukast preparations. Montelukast (sodium salt) is a potent and selective cysteinyl leukotriene 1 (CysLT1) receptor antagonist. Formulations containing ...
T72145 Montelukast dicyclohexylamine MK0476 dicyclohexylamine
Montelukast dicyclohexylamine (MK0476), a potent, selective, and orally active antagonist of the cysteinyl leukotriene receptor 1 (CysLT1), is utilized in the research of asthma, liver injury, and COVID-19. It exhibits a...
T83926 S-Geranylgeranyl-L-glutathione GGG
S-Geranylgeranyl-L-glutathione acts as a ligand for the orphan G protein-coupled receptor (GPCR) P2RY8, displaying selective affinity by inducing internalization of P2RY8 in preference to the sphingosine-1-phosphate rece...
T37980 N-methyl Leukotriene C4 N-methyl Leukotriene C4
Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione t...
T21864 BAY-u 9773
BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC 50 for CysLT 1 and CysLT 2. BAY-u9773 is used to the inhibit LT responses [1].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-03749 CYSLTR1 Protein, Human, Recombinant (His) Human E. coli
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and...
TargetMol