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Search Results for " crl4 "

Targets

5

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T22922 Lenalidomide hemihydrate TNF , Ligand for E3 Ligase , Molecular Glues
Lenalidomide hemihydrate is a TNF-α secretion inhibitor (IC50 = 13 nM). Lenalidomide hemihydrate could bound endogenous CRBN and recombinant CRBN-DNA damage binding protein-1 (DDB1) complexes.
T1642 Lenalidomide CC-5013 Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
Lenalidomide (CC-5013) is a potent inhibitor of TNF-α that, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines.
T77965 DCAF1 binder 1
DCAF1 Binder 1 selectively targets the CRL4 DCAF1 E3 ligase complex as a ligand, playing a role in targeted protein degradation (TPD) [1].
T81942 Lenalidomide sodium CC-5013 sodium
Lenalidomide (sodium), a Thalidomide derivative, serves as a molecular glue and an orally active immunomodulator. It acts as a cereblon (CRBN) ligand and triggers selective ubiquitination and subsequent degradation of th...
T21763 Lenalidomide hydrochloride
Lenalidomide hydrochloride (CC-5013 hydrochloride), a Thalidomide derivative, functions as molecular glue and serves as an orally active immunomodulator. As a ligand for the ubiquitin E3 ligase cereblon (CRBN), it facili...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04052 IL-17RB Protein, Human, Recombinant (His) Human HEK293 Cells
IL-17RB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.5 kDa and the accession number is Q9NRM6-1.
TMPY-03850 IL-17RB Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-17RB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.9 kDa and the accession number is Q9NRM6-1.
TargetMol