clk1-in-3 — TargetMol Chemicals

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Search Results for " clk1-in-3 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T72039	CLK1-IN-3		DYRK , CDK , Autophagy
	Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of 5 nM and 300 pairs higher affinity than Dyrk1A. CLK1-IN-3 also showed highly effective inhibition of Clk2 and Clk4, with IC50 values of 4...		DYRK , CDK , Autophagy
T23897	CLK1/2-IN-3	CLK1/2 inhibitor 3,CLK1/2-inhibitor-3,CLK1/2 IN 3,CLK1/2IN3	CDK
	CLK1/2-IN-3 (Cpd-3) is a potent and selective CLK1 and CLK2 inhibitor with antiproliferative activity and inhibits the activities of CLK1, CLK2, SRPK1, SRPK2, and SRPK3.CLK1/2-IN-3 induces nuclear speckle enlargement, wh...		CDK
T74805	T74805
	CLK1-IN-3 (compound 10ad) is a potent and selective Clk1 inhibitor, with an IC 50 of 5 nM and over 300-fold selectivity for Dyrk1A . CLK1-IN-3 also shows a relatively potent inhibition against Clk2 and Clk4 , with IC 50 ...
T36684	Ipivivint
	Ipivivint, a first-in-class, orally active and potent CDC-like kinase (CLK) inhibitor, inhibits CLK1 (IC50=1.4 μM), CLK2 (IC50=0.002 μM) and CLK3 (IC50=0.022 μM). Ipivivint reduces Wnt pathway signaling gene expression t...