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Search Results for " cdkn1a "

Targets

4

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T7697 BIX-01294 Histone Methyltransferase , Autophagy
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
T1959 BIX-01294 trihydrochloride BIX 01294 Histone Methyltransferase , Autophagy
BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.
T26259 Tenovin-D3 TenovinD3
Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.
T73000 SIRT2-IN-11
SIRT2-IN-11 (AEM1) is a selective inhibitor of SIRT2, demonstrating an inhibitory concentration (IC50) of 18.5 μM. It induces apoptosis in a p53-dependent manner and activates the expression of CDKN1A, PUMA, and NOXA, wh...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00578 BCCIP Protein, Human, Recombinant Human Baculovirus Insect Cells
BCCIP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.2 kDa and the accession number is AAH09771.1.
TMPY-04023 BCCIP Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
BCCIP Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 64 kDa and the accession number is AAH09771.1.
TMPY-04397 PAK-3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
PAK3 is a member of PAK proteins, a family of serine/threonine p21-activating kinases, serve as effectors of small Rho GTPases Cdc42 and RAC and have been implicated in a wide range of biological activities. There are si...
TMPH-03269 COMMD5 Protein, Rat, Recombinant (His & Myc) Rat E. coli
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the ...
TMPY-03599 RPRD1B Protein, Human, Recombinant (His) Human HEK293 Cells
RPRD1B, together with RPRD1A, can accompany RNAP II from promoter regions to 3'-untranslated regions during transcription in vivo, predominantly interact with phosphorylated RNAP II, and can reduce CTD S5- and S7-phospho...
TMPH-02131 SKP2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle pr...
TMPH-01282 ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in th...
TMPY-04542 CDK2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinas...
TMPH-01552 IRF1 Protein, Human, Recombinant (GST & His) Human Baculovirus Insect Cells
Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections,...
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