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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10747 | CDK9-IN-9 | CDK | |
CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM). | |||
T10746 | CDK9-IN-8 | CDK | |
CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM). | |||
T10745 | CDK9-IN-7 | CDK | |
CDK9-IN-7 is a highly selective and orally active CDK9/cyclin T inhibitor (IC50: 11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD: 148 nM; CDK6/cyclinD: 145 nM). | |||
T10742 | CDK9-IN-10 | CDK | |
CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2. | |||
T14918 | CDK9-IN-2 | Others , CDK | |
CDK9-IN-2 is a special CDK9 inhibitor and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours), respectively. | |||
T39354 | CDK9-IN-12 | CDK9-IN-12 | |
CDK9-IN-12 displays the optimal CDK9 inhibitory activity with an IC 50 value of 5.41 nM. | |||
T10743 | CDK9-IN-11 | CDK | |
CDK9-IN-11 is a potent CDK9 inhibitor that is the ligand for the PROTAC CDK9 Degrader-1 [1]. | |||
T10741 | CDK9-IN-1 | CDK | |
CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection (IC50: 39 nM for CDK9/CycT1). | |||
T79631 | CDK9-IN-26 | CDK | |
CDK9-IN-26, also known as compound 1, is a potent inhibitor of Cyclin-Dependent Kinase 9 (CDK9) with an IC50 value of 0.18 μM.[1] | |||
T40353 | CDK7/9-IN-1 | CDK7/9-IN-1 | |
CDK7/9-IN-1 is a specific inhibitor of cyclin-dependent kinases 7/9 (CDK7/9). It specifically targets CDK7, while also displaying inhibitory activity against CDK9. CDK7/9-IN-1 demonstrates excellent inhibitory potency ag... | |||
T36743 | CDK7/9 tide | ||
CDK7/9 tide is peptide substrate for CDK7 or CDK9[1]. [1]. Robert T, et, al. Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors. Front Chem. 2020 Feb 27; 8:1... | |||
T40047 | CDK6/9-IN-1 | CDK6/9-IN-1 | |
CDK6/9-IN-1 (compound 66) is a potent dual inhibitor of CDK 6 and CDK 9 that can be administered orally. It exhibits inhibitory activity with IC 50 values of 40.5 nM and 39.5 nM against CDK6 and CDK9, respectively. | |||
T70897 | Zotiraciclib HCl | ||
Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting M... | |||
T70988 | Ibulocydine | ||
Ibulocydine is a potent CDK inhibitor. Ibulocydine has high activity against Cdk7/cyclin H/Mat1 and Cdk9/cyclin T. Ibulocydine inhibited the growth of HCC cells more effectively than other Cdk inhibitors, including olomo... |