ccr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T25214	CCR-11	CCR11,CCR 11	Antibiotic
	CCR-11 is a tannin-containing derivative with antimicrobial activity. CCR-11 inhibits the proliferation of B. subtilis and HeLa cells. CCR-11 inhibits bacterial proliferation and bacterial cytoplasmic division by inhibit...		Antibiotic
T14688	BMS CCR2 22		CCR
	BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.		CCR
T10708	CCR1 antagonist 6		CCR
	CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).		CCR
T10715	CCR6 inhibitor 1		CCR
	CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively). CCR6 is associated with both autoimmune and non-autoimmune diseases, so CCR6 inhibitor ...		CCR
T11481	GSK2239633A		CCR
	GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.		CCR
T10156	CCR3 antagonist 1		CCR
	CCR3 antagonist 1 is a potent CCR3 antagonist, used for the research of inflammatory and immunologic diseases.		CCR
T13114	CCR2 antagonist 4	Teijin compound 1	CCR
	CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM).		CCR
TQ0103	INCB3344		CCR
	INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis act...		CCR
T4300	AZD2098		CCR
	AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.		CCR
TQ0283	RS102895		CCR
	RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.		CCR
T5384	RS 504393		CCR
	RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).		CCR
T14900	CCR2-RA-[R]		CCR
	CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).		CCR
T10712	CCR2 antagonist 3	AZD-2927,AZD2927	CCR
	CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.		CCR
T4674	SB297006	SB 297006	CCR
	SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...		CCR
T24700	R243	R 243,R-243	CCR
	R243 is CCR8 signaling and chemotaxis inhibitor.		CCR
T10425	AZ084		CCR
	AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.		CCR
T6413	Bindarit	AF2838	CCR
	Bindarit (AF2838) displays specific inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.		CCR
T16111	ML604086		CCR
	ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor of CCR8. It also inhibiting CCL1 binding to CCR8 on circulating T-cells.		CCR
T16091	MK-0812 Succinate		Others , CCR
	MK-0812 Succinate is an effective and selective CCR2 antagonist. It also has a high affinity at CCR2.		Others , CCR
T11699	J-113863		CCR
	J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor...		CCR