Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 76.00 | |
5 mg | In stock | $ 187.00 | |
10 mg | In stock | $ 278.00 | |
25 mg | In stock | $ 469.00 | |
50 mg | In stock | $ 677.00 | |
100 mg | In stock | $ 943.00 | |
500 mg | In stock | $ 1,880.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 198.00 |
Description | CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM). |
Targets&IC50 | CCR2b:180 nM |
In vivo | Vp-TSL targets specifically aortic plaque endothelial VCAM-1 and CCR2 antagonist 4 reduces the mouse monocyte/macrophage cell line (RAW 264.7) adhesion/ infiltration into the aorta in ApoE-deficient mice[3]. |
Synonyms | Teijin compound 1 |
Molecular Weight | 439.86 |
Formula | C21H21ClF3N3O2 |
CAS No. | 226226-39-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (113.67 mM)
You can also refer to dose conversion for different animals. More
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CCR2 antagonist 4 226226-39-7 Immunology/Inflammation Microbiology/Virology CCR CCR-2 antagonist 4 CCR2b chemokines chemotaxis Inhibitor Teijin compound 1 inhibit inflammatory MCP-1 chronic CC chemokine receptor Teijin compound1 Teijin compound-1 inhibitor