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Search Results for " cbr "

Targets

9

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T14884 CBR-5884 Others , Dehydrogenase
CBR-5884 is an selective, active of phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with h...
T40063 CBR-470-1 Nrf2
CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protect...
T36037 CBR-470-2
CBR-470-2, a glycine-substituted analog, exhibits the capacity to activate NRF2 signaling, making it a valuable compound for investigating glycolysis modulation in scientific research [1].
T26963 CBR-2092 TNP2092,CBR2092,TNP-2092,TNP 2092
CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor. CBR-2092 exhibited rifampin-like potency as an inhibitor of RNA polymerase, was an equipotent (balanced) inhibitor of DNA gyrase and DNA topoisom...
T61192 CBR-6672
CBR-6672, a type II NADH dehydrogenase inhibitor, demonstrates potent antimycobacterial activity against mycobacterium tuberculosis (Mtb) with a minimum inhibitory concentration (MIC) of 0.14 μM [1].
T61035 CBR-3465
CBR-3465 is an inhibitor of mycobacterium tuberculosis (Mtb) type II NADH dehydrogenase. The MIC of CBR-3465 against Mtb is 0.16 μM [1].
T62583 CBR Agonist-1
CBR Agonist-1 (27a-cis) is a cannabinoid receptor (CBR) agonist that acts on CB1R (Ki: 0.18 μM) and CB2R (Ki: 1.22 μM). CBR Agonist-1 (27a-cis) can be used to study endogenous cannabinoid system-related diseases.
T62584 CBR Agonist-2
CBR Agonist-2 is a CB1 agonist (CB1R; CB1 ligand) (EC50: 960 nM, Ki: 970 nM). CBR Agonist-2 is a promising tool for the study of endogenous cannabinoid system-related diseases involving hCB1R.
T81262 Rocbrutinib
Rocbrutinib is a Bruton's tyrosine kinase (BTK) inhibitor that exhibits antineoplastic properties [1].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01039 CBR1 Protein, Human, Recombinant (E. coli, His) Human E. coli
CBR1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.2?kDa and the accession number is P16152.
TMPH-01040 CBR1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
CBR1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.2 kDa and the accession number is P16152.
TMPY-03867 CBR3 Protein, Human, Recombinant (His) Human E. coli
CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate...
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