15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18485 | NH2-C4-NH-Boc | Others , PROTAC Linker | |
NH2-C4-NH-Boc (compound 15) is a PROTAC linker belonging to the Alkyl/ether class. NH2-C4-NH-Boc can be used to synthesize a series of PROTAC molecules. | |||
T36841 | IPI-9119 | Fatty Acid Synthase | |
IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM). | |||
T14584 | Biotin-PEG2-C4-alkyne | Others | |
Biotin-PEG2-C4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sy... | |||
T18624 | NH2-Ph-C4-acid-NH2-Me | PROTAC Linker 31 | Others |
NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound utilized for the synthesis of PROTACs. [1] | |||
T17910 | (S,R,S)-AHPC-PEG2-C4-Cl | E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl | Others |
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-bas... | |||
T18623 | Boc-NH-PEG2-C2-amido-C4-acid | PROTAC Linker 30 | Others |
Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1]. | |||
T27601 | IMTPPE | SID-3712502,SID 3712502,SID3712502 | |
IMTPPE inhibits transcriptional activity and protein level of AR in C4-2 prostate cancer cells. It also inhibits AR-target gene expression. | |||
T37564 | C4 Ceramide (d18:1/4:0) | C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0) | |
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used... | |||
T18533 | PEG3-C4-OBn | Others | |
PEG3-C4-OBn, a polyethylene glycol (PEG)-based PROTAC linker, is utilized in crafting the PROTAC SGK3 degrader-1, a potent SKG3 degrader leveraging PROTAC technology [1][2]. | |||
T62031 | SARS-CoV-2 nsp13-IN-4 | ||
SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective small-molecule inhibitor of nsp13 helicase. SARS-CoV-2 nsp13-IN-4 inhibits the ssDNA+ ATPase activity of nsp13 with an IC 50 of 57 μM. SARS-CoV-2 nsp13-IN-4 can pr... | |||
T17906 | Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc | E3 Ligase Ligand-Linker Conjugates 53,Cereblon Ligand-Linker Conjugates 20 | Others |
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a novel synthesized conjugate compound functioning as an E3 ligase ligand-linker in PROTAC technology. This compound incorporates a Pomalidomide-derived cereblon ligand, whic... | |||
T37506 | MCTR2 | MCTR2 | |
Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is ... | |||
T35790 | Palmitic acid-1,2,3,4-13C4 | Palmitic Acid-13C (C1, C2, C3, and C4 labeled) | |
Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20%... | |||
T37736 | N-cis-hexadec-9Z-enoyl-L-Homoserine lactone | N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone | |
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm f... | |||
T37741 | N-hexadecanoyl-L-Homoserine lactone | C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone | |
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm fo... |