c3b — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP2228	C3bot(154-182)	C3bot (154-182)	Others
	transferase-deficient neurotrophic fragment of clostridial C3 protein
T82798	C3bot(154-182) TFA
	C3bot(154-182) TFA, a C3 peptide, facilitates spinal cord injury recovery by promoting regenerative growth of descending fiber tracts. It serves as a potential therapeutic agent to support axonal protection and/or repair...
T77089	Mirococept
	Mirococept (APT070), an antibody designed to target the complement system components C3b/C4b and act as a membrane-localizing C3 convertase inhibitor, effectively diminishes the release of C-peptide and pro-inflammatory ...

Recombinant Proteins

Species：

Expression System：

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Cat No.	Product Name	Species	Expression System
TMPY-05731	Complement C3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.43 kDa and the accession number is P01024.
TMPH-03273	Complement factor I Protein, Rat, Recombinant (His & Myc)	Rat	Baculovirus Insect Cells
	Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 69.2 kDa and the accession number is Q9WUW3.
TMPK-00776	Complement factor I Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P...
TMPH-01135	CR1 Protein, Human, Recombinant (GST)	Human	E. coli
	CR1 Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPK-01023	Complement factor I Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P...
TMPJ-00501	CLEC3B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind...
TMPY-00353	LRRC3B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LRRC3B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.7 kDa and the accession number is A1LNH5.
TMPJ-01321	MAP1LC3B Protein, Human, Recombinant	Human	E. coli
	Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in t...
TMPY-03749	LC3B Protein, Human, Recombinant (His)	Human	E. coli
	MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 beta, also known as LC3B) is a Protein Coding gene. The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are in...
TMPY-00088	LRRC3B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LRRC3B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is A1LNH5.
TMPH-03038	Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)	Naja kaouthia	E. coli
	Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to fo...
TMPK-00570	CD46 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in prev...
TMPH-03559	Sbi Protein, S. aureus, Recombinant (Avi & His & MBP), Biotinylated	Staphylococcus aureus	E. coli
	Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b ...
TMPH-03272	Complement factor D Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classi...
TMPK-00532	CD46 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in prev...
TMPH-02845	Properdin Protein, Mouse, Recombinant (His & Myc)	Mouse	HEK293 Cells
	A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Comple...
TMPH-02844	Properdin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Comple...
TMPH-02921	SUSD4 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classic...
TMPH-03271	Complement factor D Protein, Rat, Recombinant (His & Myc)	Rat	HEK293 Cells
	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classi...
TMPH-03578	SCIN Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a ...
TMPH-02606	CR1L Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor,...
TMPH-00534	Gelatinase Protein, Enterococcus faecalis, Recombinant (His & SUMO)	Enterococcus faecalis	E. coli
	Metalloprotease capable of the hydrolysis of insoluble hydrophobic substrates. Hydrolyzes azocoll and gelatin and, at a lower rate, soluble and insoluble collagens. Does not cleave short synthetic peptides. Preferentiall...
TMPJ-00809	CFH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal ...