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Search Results for " branaplam "

4

Compounds

Cat No. Product Name Synonyms Targets
T4641 Branaplam LMI 070,NVS-SM1 Others , Potassium Channel , DNA/RNA Synthesis
Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.
T26893 Branaplam mesylate (1562338-42-4 free base) LMI070,Branaplam mesylate,LMI 070,LMI-070
Branaplam is a highly potent, selective and orally active SMN2 splicing modulator. Branaplam increases the amount of functional SMN protein produced by the SMN2 gene through modifying its splicing.
T62381 Branaplam hydrochloride
Branaplam (LMI070; NVS-SM1) hydrochloride is a selective, orally active SMN2 splicing modulator that acts on SMN (EC50: 20 nM). branaplam hydrochloride inhibits hERG (IC50: 6.3 μM). In a mouse model of severe spinal musc...
T79717 MHTT-IN-2 Huntingtin
mHTT-IN-2 (compound 27) is a potent inhibitor of mutant huntingtin protein (mHTT), with an EC50 value of 0.066 μM. It specifically modulates the splicing of HTT RNA exons [49-50], acting as a splicing regulator for the H...
TargetMol