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Search Results for " bmi-1 "

8

Compounds

Cat No. Product Name Synonyms Targets
T12575 Unesbulin PTC596 Apoptosis , BMI-1
Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).
T16680 PTC-028 Apoptosis , BMI-1
PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspas...
T2345 PTC-209 PTC209,PTC 209 BMI-1 , Autophagy
PTC-209 is a potent and selective BMI-1 inhibitor.
TN2507 1,6,7-Trihydroxyxanthone DNA/RNA Synthesis
1,6,7-Trihydroxyxanthone has anti-cancer activity ,at least in part, through the activation of miR-218 and suppression of Bmi-1 expression; can suppress cell growth and induce apoptosis in liver cancer cells.
T62617 QW24
QW24 down-regulates BMI-1, exhibits potent antitumour effects and is used as an effective therapeutic agent in the treatment of clinical colorectal cancer.
T82852 BMI-Glu
BMI-Glu, a selective γ-glutamyl transpeptidase (GGT) fluorescent probe, exhibits a Michaelis constant (Km) of 69.63 µM and is characterized by its high sensitivity, good water solubility, and biocompatibility [1].
T63374 SH498
SH498 is a novel Bmi-1-mediated anti-tumor agent with significant anti-proliferative effects.
T6178 PTC-209 hydrobromide PTC-209 HBr BMI-1 , Autophagy
PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).
TargetMol