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Cat No. | Product Name | Synonyms | Targets |
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T35666 | PRGL493 | Others | |
PRGL493 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4).1It inhibits formation of arachidonoyl-CoA (AA-CoA) from arachidonic acid in, as well as the proliferation and migration of, PC3 and MDA-MB-231 cancer c... | |||
T79639 | Lepadin H | Ferroptosis | |
Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing lipid peroxidation. It simultaneously decreases SLC7A11 and GP... | |||
T37487 | 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE | ||
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE b... | |||
T79638 | Lepadin E | Glutathione Peroxidase | |
Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway. By elevating p53 and repressing SLC7A11 and GPX4 expression, it heightens ROS and lipid peroxidation... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02764 | ACSL4 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
ACSL4 Protein, Mouse, Recombinant (His) is expressed in E. coli. |