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Search Results for " azd5363 "

2

Compounds

Cat No. Product Name Synonyms Targets
T1920 Capivasertib AZD5363 Akt , PKA , mTOR , Autophagy
Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity. Capivasertib has antitumor activity for the treatment of breast cancer.
T71242 AZD-1897
AZD-1897 is an ATP-competitive pan-PIM inhibitor. When combined with the Akt inhibitor AZD5363, AML cells from putative leukaemia stem cells incur a reduction in levels of the anti-apoptotic protein MCL1. The combination...
TargetMol