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Cat No. | Product Name | Synonyms | Targets |
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T7656 | Apelin-13 | ||
Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ... | |||
TP2092L | Apelin-17 (human, bovine) acetate | Apelin-17 (human, bovine) acetate(217082-57-0 free base) | HIV Protease |
Apelin-17 (human, bovine) acetate is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94). | |||
T7847 | Apelin-13 triTFA(217082-58-1(free base)) | Others | |
Apelin-13 triTFA is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. | |||
TP1260 | [Pyr1]-Apelin-13 | [pGlu1]-Apelin-13 | Apelin receptor |
[Pyr1]-Apelin-13 ([pGlu1]-Apelin-13) is a potent and selective endogenous Apelin receptor (APJ) agonist. | |||
T39823L | Apelin-12 acetate | Apelin-12 acetate (229961-08-4 Free base) | Apelin receptor , p38 MAPK , JNK |
Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 MAPK signaling pathway of the apoptosis-related MAPKs family, thus offering protection to neurons. | |||
TP1424 | Apelin-13 TFA (217082-58-1 free base) | Apelin-13 TFA | |
Apelin-13 is an endogenous ligand of APJ receptor, and the EC 50 value of activated G protein coupled receptor is 0.37 nM. | |||
T39823 | Apelin-12 | ||
Apelin-12 is a highly potent C-terminal fragment of a polypeptide that exhibits a strong affinity towards the orphan receptor APJ. It plays a role in maintaining body fluid balance and regulating feeding control in the c... | |||
T35374 | (Ala13)-Apelin-13 | (Ala13)-Apelin-13 | Others |
(Ala13)-Apelin-13 is a useful organic compound for research related to life sciences. The catalog number is T35374 and the CAS number is 568565-11-7. | |||
TP2094 | Apelin-36(rat, mouse) | Apelin-36 (rat, mouse) | |
Endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC50 = 5.4 nM) and potently inhibits cAMP production in vitro (EC50 = 0.52 nM). Involved in regulation of cardiov... | |||
T34516 | Sapelin B | NSC 270047,NSC270047,NSC-270047 | |
Sapelin B is a triterpenoid. | |||
T27157 | Dezapelisib | INCB-040093,INCB 040093,INCB040093 | |
Dezapelisib is an orally bioavailable, selective inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinases (PI3K). INCB040093 prevents both the production of the second messeng... | |||
T75783 | Apelin-36(human) TFA | ||
Apelin-36(human) TFA, an endogenous agonist of the orphan G protein-coupled receptor APJ, exhibits a potent EC50 of 20 nM and high affinity (pIC5 50 = 8.61) for human APJ receptors in HEK 293 cells. It is involved in sig... | |||
T75785 | Apelin-17(human, bovine) TFA | ||
Apelin-17(human, bovine) TFA is an endogenous agonist of the orphan G protein-coupled receptor APJ. This compound demonstrates affinity for human APJ receptors on HEK 293 cells, evidenced by a pIC50 value of 9.02. Additi... | |||
TP2093 | Apelin-36(human) | Apelin-36 (human) | |
Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61). Involved in regulation of cardiovascular function, ... | |||
T34515 | Sapelin A | NSC-270046,NSC 270046,NSC270046 | |
Sapelin A is a terpenoid. | |||
T10346 | Apelin agonist 1 | Others | |
Apelin agonist 1 is an oral selective apelin agonist AM-2995, an agonist of the APJ (APLNR, angiotensin receptor like-1) receptor. It may be used in the treatment of cardiovascular conditions. | |||
T75784 | Apelin-36(rat, mouse) TFA | ||
Apelin-36(rat, mouse) TFA, an endogenous agonist for the orphan G protein-coupled receptor APJ, exhibits a strong affinity for APJ receptors with an IC 50 of 5.4 nM and effectively inhibits cAMP production with an EC 50 ... | |||
T35374L | (Ala13)-Apelin-13 acetate | Apelin receptor | |
(Ala13)-Apelin-13 acetate, an APJ antagonist, modulates CRF-induced enhanced colonic motility, visceral sensation, and gut barrier. | |||
TP2092 | Apelin-17(human, bovine) | Apelin-17 (human, bovine) | |
Endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94). | |||
T78109 | (Ala13)-Apelin-13 TFA | ||
'(Ala13)-Apelin-13 TFA acts as a potent antagonist of the apelin receptors (APJ) and impedes gastric motility via the vagal cholinergic pathway [1].' |
Cat No. | Product Name | Synonyms | Targets |
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T4S1869 | 12-Epinapelline | Others | |
12- Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of voltage gated Na+ channels are responsible for these obser... |
Cat No. | Product Name | Species | Expression System |
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TMPK-01222 | APLN Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized... | |||
TMPK-01221 | APLN Protein, Mouse, Recombinant (hFc & Avi), Biotinylated | Mouse | HEK293 |
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized... | |||
TMPK-01236 | APLN Protein, Human, Recombinant (hFc) | Human | HEK293 |
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized... |