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Search Results for " apel "

Targets

20

Compounds

1

Natural Products

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T7656 Apelin-13
Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ...
TP2092L Apelin-17 (human, bovine) acetate Apelin-17 (human, bovine) acetate(217082-57-0 free base) HIV Protease
Apelin-17 (human, bovine) acetate is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).
T7847 Apelin-13 triTFA(217082-58-1(free base)) Others
Apelin-13 triTFA is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM.
TP1260 [Pyr1]-Apelin-13 [pGlu1]-Apelin-13 Apelin receptor
[Pyr1]-Apelin-13 ([pGlu1]-Apelin-13) is a potent and selective endogenous Apelin receptor (APJ) agonist.
T39823L Apelin-12 acetate Apelin-12 acetate (229961-08-4 Free base) Apelin receptor , p38 MAPK , JNK
Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 MAPK signaling pathway of the apoptosis-related MAPKs family, thus offering protection to neurons.
TP1424 Apelin-13 TFA (217082-58-1 free base) Apelin-13 TFA
Apelin-13 is an endogenous ligand of APJ receptor, and the EC 50 value of activated G protein coupled receptor is 0.37 nM.
T39823 Apelin-12
Apelin-12 is a highly potent C-terminal fragment of a polypeptide that exhibits a strong affinity towards the orphan receptor APJ. It plays a role in maintaining body fluid balance and regulating feeding control in the c...
T35374 (Ala13)-Apelin-13 (Ala13)-Apelin-13 Others
(Ala13)-Apelin-13 is a useful organic compound for research related to life sciences. The catalog number is T35374 and the CAS number is 568565-11-7.
TP2094 Apelin-36(rat, mouse) Apelin-36 (rat, mouse)
Endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC50 = 5.4 nM) and potently inhibits cAMP production in vitro (EC50 = 0.52 nM). Involved in regulation of cardiov...
T34516 Sapelin B NSC 270047,NSC270047,NSC-270047
Sapelin B is a triterpenoid.
T27157 Dezapelisib INCB-040093,INCB 040093,INCB040093
Dezapelisib is an orally bioavailable, selective inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinases (PI3K). INCB040093 prevents both the production of the second messeng...
T75783 Apelin-36(human) TFA
Apelin-36(human) TFA, an endogenous agonist of the orphan G protein-coupled receptor APJ, exhibits a potent EC50 of 20 nM and high affinity (pIC5 50 = 8.61) for human APJ receptors in HEK 293 cells. It is involved in sig...
T75785 Apelin-17(human, bovine) TFA
Apelin-17(human, bovine) TFA is an endogenous agonist of the orphan G protein-coupled receptor APJ. This compound demonstrates affinity for human APJ receptors on HEK 293 cells, evidenced by a pIC50 value of 9.02. Additi...
TP2093 Apelin-36(human) Apelin-36 (human)
Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61). Involved in regulation of cardiovascular function, ...
T34515 Sapelin A NSC-270046,NSC 270046,NSC270046
Sapelin A is a terpenoid.
T10346 Apelin agonist 1 Others
Apelin agonist 1 is an oral selective apelin agonist AM-2995, an agonist of the APJ (APLNR, angiotensin receptor like-1) receptor. It may be used in the treatment of cardiovascular conditions.
T75784 Apelin-36(rat, mouse) TFA
Apelin-36(rat, mouse) TFA, an endogenous agonist for the orphan G protein-coupled receptor APJ, exhibits a strong affinity for APJ receptors with an IC 50 of 5.4 nM and effectively inhibits cAMP production with an EC 50 ...
T35374L (Ala13)-Apelin-13 acetate Apelin receptor
(Ala13)-Apelin-13 acetate, an APJ antagonist, modulates CRF-induced enhanced colonic motility, visceral sensation, and gut barrier.
TP2092 Apelin-17(human, bovine) Apelin-17 (human, bovine)
Endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).
T78109 (Ala13)-Apelin-13 TFA
'(Ala13)-Apelin-13 TFA acts as a potent antagonist of the apelin receptors (APJ) and impedes gastric motility via the vagal cholinergic pathway [1].'
Cat No. Product Name Synonyms Targets
T4S1869 12-Epinapelline Others
12- Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of voltage gated Na+ channels are responsible for these obser...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-01222 APLN Protein, Mouse, Recombinant (hFc) Mouse HEK293
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized...
TMPK-01221 APLN Protein, Mouse, Recombinant (hFc & Avi), Biotinylated Mouse HEK293
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized...
TMPK-01236 APLN Protein, Human, Recombinant (hFc) Human HEK293
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized...
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