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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8108 | Blu-782 | ALK2-IN-1 | ALK |
Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM) | |||
T79020 | ALK2-IN-5 | ||
ALK2-IN-5, a pyrazolopyrimidine compound, serves as an inhibitor of ALK2 and FGFR, targeting disorders linked with their activity, including cancer [1]. | |||
T81410 | Prafnosbart | DS-6016A | |
Prafnosbart (DS-6016A) is a humanized IgG1-kappa monoclonal antibody targeting ACVR1 (activin A receptor type 1, ACVRLK2, ALK2, ACVR1A, SKR1), utilized in research on bone metabolism disorders [1]. | |||
T62783 | RIPK2-IN-1 | ||
RIPK2-IN-1 (compound 18f) is a potent inhibitor of RIPK2 (IC50: 51 nM) and also inhibits ALK2 (IC50: 5 nM). | |||
T81740 | Multi-kinase-IN-6 | Trk receptor | |
Multi-kinase-IN-6 (compound 10e) is a multikinase inhibitor that effectively impedes the activity of TrkA, ALK2, c-KIT, EGFR, PIM1, CK2α, CHK1, and CDK2. It exhibits antiproliferative effects on MCF7, HCT116, and EKVX ca... |