3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13410 | ZLDI-8 | Apoptosis , Phosphatase , Gamma-secretase , Immunology/Inflammation related | |
ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein. | |||
TP2108 | TAPI 2 | ||
ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes. | |||
TP2107 | TAPI 0 | ||
ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth. |