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Search Results for " ache-in-7 "

8

Compounds

Cat No. Product Name Synonyms Targets
T61936 AChE-IN-7
AChE-IN-7 (Compound 16) is a selective and effective acetylcholinesterase inhibitor with IC50 of 0.045 μM and 19.68 μ M for eeAChE and eeBuChE, respectively. AChE-IN-7 has high permeability of blood-brain barrier. AChE-I...
T8585 TA-03 7-Methoxytacrine,7-Meota AChE
TA-03 (7-Meota) is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.
T3S1416 Decursin Decursinol angelate,(+)-Decursin Apoptosis , PKC
1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ...
T6S0653 Linarin Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine TNF , AChE
1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat...
T62062 MAO-B-IN-7
MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor. MAO-B-IN-7 exhibits IC50 s of 41 nM, 87 nM and 0.3 μM for human AChE, electric eel AChE and MAO-B, respectively. MAO-B-IN-7 effectively a...
T61050 BChE-IN-7
BChE-IN-7 (compound 13) is a potent, selective, and reversible inhibitor of AChE and BChE. The IC50 value of BChE-IN-7 for BChE is 0.06 μM. BChE-IN-7 is able to cross the blood-brain barrier and protect neuronal-like cel...
T7037 7-Acetoxy-4-methylcoumarin MU-Ac Others
7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell membrane environmental mimic, to study su...
T36639 Donecopride (fumarate hydrate)
Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= ...
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