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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6732 | WYE-687 | p38 MAPK , PI3K , Src , mTOR | |
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fol... | |||
T72270 | WYE-687 dihydrochloride | ||
WYE-687 dihydrochloride is an ATP-competitive inhibitor of mTOR, demonstrating potent activity with an IC 50 value of 7 nM. It effectively suppresses the activation of both mTORC1 and mTORC2. Additionally, WYE-687 exhibi... |